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High expression of PIG11 correlates with poor prognosis in …
https://pubmed.ncbi.nlm.nih.gov/33603857
P53-induced gene 11 (PIG11) is an early transcription-related target of p53 that is involved in cell apoptosis and tumor development. However, its biological function in gastric cancer (GC) tissues and relationship with the prognosis of patients with GC have remained elusive. In the present retrospe …
Possible roles of a tumor suppressor gene PIG11 in …
https://pubmed.ncbi.nlm.nih.gov/19333544
The above results demonstrated that the PIG11 gene may be involved in As(2)O(3)-induced apoptosis in HepG2 cells and suggested that the adaptive response of PIG11 expression is one of the important factors in enhancing cell sensitivity to As(2)O(3)-induced apoptosis.
PIG11 protein binds to DNA in sequence-independent manner …
https://www.sciencedirect.com/science/article/pii/S0006291X07007164#!
PIG11 (p53-induced protein 11) is one of tumor suppressor p53-induced protein (PIGs), first reported and named by Polyak et al. , which are early transcriptional targets of p53 detected by SAGE technique after overexpression of p53 and before the onset of morphological signs of apoptosis.Recent investigations suggested PIG11 may be one of candidate tumor suppressor gene from chromosome 11p11.2 …
PIG11 over-expression predicts good prognosis and induces …
https://www.sciencedirect.com/science/article/pii/S0753332218318444
PIG11 over-expression can alter oxidation-reduction metabolic pathways and metabolites, such as varieties in NADPH oxidase in the membrane . ROS generation may be related to the activation of the NF-κB family , which is composed of RelA/p65, c-Rel, RelB, p52, and p50 . Therefore, ROS elevation by PIG11 can be a result of either indirect or …
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https://www.nascar.com/fantasy
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